Because finasteride is able to inhibit the conversion of testosterone to 5α
The short answer is yes
The present study was an updated meta-analysis that aimed to confirm the efficacy and
Background: Finasteride and dutasteride are inhibitors of the enzyme 5-alpha-reductase
Finasteride and dutasteride block the conversion of testosterone into DHT which
The drug treatments include finasteride which inhibits the conversion of testosterone to dihydrotestosterone
It is a byproduct of testosterone, formed when the enzyme 5-alpha reductase breaks down the hormone
Dutasteride inhibits both type 1 and type 2 5α-reductase isoenzymes, whereas
The administration of finasteride 5 mg/day for the treatment of BPH results in 60-93% reduction in circulating DHT levels from the baseline [ 1] with a 15 - 25% rise in testosterone levels
The search formula was as follows: “dutasteride, finasteride, androgenetic alopecia, and RCT”
October 26, 2022 Azam Qureshi, MD
Both finasteride and dutasteride block the 5-alpha reductase enzyme needed to convert testosterone into dihydrotestosterone
In the animal model, inhibition of 5α-Rs types 1 and 2 impeded
Finasteride inhibits Type 2 and Type 3, while dutasteride inhibits all 3 types
In this study, men with BPH were randomized (allocation concealed) to doxazosin (4 to 8 mg per day, as tolerated), finasteride (5 mg orally per day), a combination of the drugs, or neither
Mechanism of Action
Weekends off
dutasteride (Avodart) finasteride (Proscar, generic) How they work