17 mg/mL at 25°C) and slightly soluble in 0
The too‐early dose intensification may have produced lamotrigine‐induced blood dyscrasia
Before you start
Lamotrigine initiation immediately after mRNA vaccination may be a leukopenia risk factor
Lamotrigine has been repeatedly reported to cause hematologic toxicities, which may be associated with high initial doses or excessive escalation
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in 2007 ended with drug discontinuation due to the exacerbation of leukopenia and neutropenia despite the attempts to modify
1177/070674370505000412
Persistent depressive disorder (PDD) was first introduced in the Diagnostic and Statistical Manual of Mental Disorders 5th edition (DSM‐5), which encompasses
Several psychotropic drugs, including clozapine, are known to cause agranulocytosis and this may lead to a fatal condition
The WBC count and absolute neutrophil count (ANC) at the time of admission were 4,400 cells/mm 3 and 2240 cells/mm 3, respectively
2012 May;42(5):584-5
Leukopenia is almost always associated with a reduction in a specific type of white blood cell (neutrophil)
This article presents the case of a patient who developed significant leukopenia after lamotrigine intake (with lower limit of the norm of neutrophils; granulocytes count was about 1,500 per mm3 but did not fall to lower values)
Patients with leukocytosis and no other signs of systemic inflammatory response syndrome do not require blood cultures
Neutrophils are white blood cells that act as your immune system’s first line of defense
Infection, drugs, malignancy, megaloblastosis, hypersplenism and Adverse lamotrigine effects are more likely with concomitant use of antiepileptic drugs, rapid dose titration, and multiple drug use, highlighting the importance of measuring its concentration
Chronic leukopenia associated with taking
We report the case of a 15-year-old Chinese female epileptic patient weighing 60 kg who developed combined asymptomatic
The disease worsened over a period of about 4 years
Publication types However, leukopenia increases your risk of infections, and you will have symptoms if you develop one
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The plasma concentration of lamotrigine has not been measured in this case
Weeks 3 and 4: 25 mg every day
Focal symptoms of infection may be muted, but fever is present during most serious infections
The disease worsened over a period of about 4 years